Bonassar, Lawrence

Associate Professor

research

research and scholarship focus

Dr. Bonassar's research group focuses on the regeneration and analysis of musculoskeletal tissues, including bone and cartilage. The approach involves a multidisciplinary strategy using techniques in biomechanics, biomaterials, cell biology, and biochemistry. Applications of this technology include the repair of articular cartilage, intervertebral disc, trachea and craniofacial defects. At the cellular level, this work focuses on understanding the interactions of chondrocytes, fibroblasts and stem cells with biomaterials. This includes grafting of cell adhesion peptides to polymers and characterizing the effects of these alterations on the way in which cells sense their environment.

Current Projects

  • Tissue Injection Molding
  • Microfabrication of Vascular Hydrogels
  • Analysis of Molecular Mechanisms of Cartilage Lubrication
  • Modified Hydrogels to Study Chondrocyte Mechanotransduction
  • Interfacial Cartilage Repair

research areas

affiliations

faculty appointment in

member of graduate field

other Cornell affiliations

teaching

teaches

background

educational background

Ph.D. 1995 - MIT, Materials Science and Engineering
M.S. 1991 - MIT, Materials Science and Engineering
B.S. 1989 - Johns Hopkins, Materials Science and Biomedical Engineering

professional background

Dr. Bonassar joined Cornell University in 2003 after five years on the faculty of the Center for Tissue Engineering at the University of Massachusetts Medical School. He completed postdoctoral fellowships in the Orthopaedic Research Laboratory at the Massachusetts General Hospital and in the Center for Biomedical Engineering at the Massachusetts Institute of Technology.

publications